000 04854nam a22005295i 4500
001 978-3-642-00534-3
003 DE-He213
005 20201213203822.0
007 cr nn 008mamaa
008 100301s2009 gw | s |||| 0|eng d
020 _a9783642005343
_9978-3-642-00534-3
024 7 _a10.1007/978-3-642-00534-3
_2doi
050 4 _aTA405-409.3
050 4 _aQA808.2
072 7 _aTG
_2bicssc
072 7 _aTEC009070
_2bisacsh
072 7 _aTEC021000
_2bisacsh
082 0 4 _a620.1
_223
100 1 _aGefen, Amit.
_eeditor.
245 1 0 _aBioengineering Research of Chronic Wounds
_h[electronic resource] :
_bA Multidisciplinary Study Approach /
_cedited by Amit Gefen.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2009.
300 _aIX, 449 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v1
505 0 _aPrinciples of ChronicWound Pathology, Pathomechanics and Healing Response -- Fundamentals of Pressure, Shear and Friction and Their Effects on the Human Body at Supported Postures -- Mechanobiology of Cutaneous Wound Healing and Scarring -- Cell Migration along the Basement Membrane during Wound Repair. The Corneal Endothelium as a Model System -- The Importance of the Microenvironment of Support Surfaces in the Prevalence of Pressure Ulcers -- Mathematical Modeling of Chronic Wounds and Wound Healing -- Partial Differential Equations for Modelling Wound Geometry -- A Suite of Continuum Models for Different Aspects in Wound Healing -- Computer Methods for Studying Biomechanical Conditions at Chronic Wound Sites: From Tissue to Cellular Scales -- MRI Integrated with Computational Methods for Determining Internal Soft Tissue Loads as Related to Chronic Wounds -- A Finite-Element Biomechanical Model for Evaluating Buttock Tissue Loads in Seated Individuals with Spinal Cord Injury -- Finite Element and Animal Studies of Scar Contractions Leading to Chronic Wounds -- Cellular Deformations under Compression in Cells Involved in Deep Tissue Injury -- Tissue-Engineered Constructs for Studying and Repairing Chronic Wounds -- Tissue Engineered Models: A Valuable Tool in Pressure Ulcer Research -- Tissue-Engineered Models for the Study of Cutaneous Wound-Healing -- Tissue-Derived Materials for Adipose Regeneration -- Biochemical Markers for Early Identification and for Monitoring the Healing of Chronic Wounds -- Clinical and Molecular Perspectives of Deep Tissue Injury: Changes in Molecular Markers in a Rat Model -- Proteomic Approaches for Studying the Phases of Wound Healing -- Innovative Technologies and Devices in the Diagnosis and Treatment of Chronic Wounds -- Bioengineering Techniques in Wound Assessment -- Optical Non-invasive Characterization of Chronic Wounds -- Regenerative Wound Healing via Biomaterials -- Abdominal Wall Hernias and Biomaterials.
520 _aPressure-related chronic wounds are an important health concern that affects millions of patients and accumulates billions in annual costs. These wounds may occur when soft tissues are mechanically compressed between bony prominences and a supporting surface. This book gives a complete and quantitative explanation of the mechanobiology which causes chronic wounds. The reviews give an overall picture on all length scales of the phenomenon, starting from musculoskeletal biomechanics to the modeling of soft tissues and their interaction with bones. At the microscopic levels, it thoroughly reviews experiments and modeling of cellular forces and molecular processes that occur during injury and healing, including the integrity of living cells subjected to sustained mechanical forces and deformations. The results allow a complete picture of the tolerance of human tissues to sustained loads, and an understanding of the risk for onset of chronic wounds. Hence, this book is also valuable for all professionals involved in the prevention and treatment of chronic wounds.
650 0 _aEngineering.
650 0 _aMedicine.
650 0 _aBiochemistry.
650 0 _aBiology
_xData processing.
650 0 _aMaterials.
650 1 4 _aEngineering.
650 2 4 _aContinuum Mechanics and Mechanics of Materials.
650 2 4 _aMolecular Medicine.
650 2 4 _aMedical Biochemistry.
650 2 4 _aComputer Appl. in Life Sciences.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642005336
830 0 _aStudies in Mechanobiology, Tissue Engineering and Biomaterials,
_x1868-2006 ;
_v1
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-00534-3
912 _aZDB-2-ENG
950 _aEngineering (Springer-11647)
999 _c23004
_d23004